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Legal status
Legal status
CAS Number
  • none
PubChem CID
Chemical and physical data
Formula C24H32N2O2
Molar mass 380.53 g·mol−1
3D model (JSmol)

4-Methoxybutyrfentanyl (also known as 4-MeO-BF) is an opioid analgesic that is an analog of butyrfentanyl and has been sold online as a designer drug.[1][2][3]

Side effects

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[4]

Life-threatening adverse reactions have been observed.[5]

Legal status

4-Methoxybutyrfentanyl is illegal in Sweden as of 26. January 2016.[6]

4-Methoxybutyrfentanyl is a Schedule I controlled drug in the USA since 1. February 2018.[7]

See also


  1. ^ "4-MeO-Butyrfentanyl". Cayman Chemical. 
  2. ^ "4-Methoxybutyrfentanyl". New Synthetic Drugs Database. 
  3. ^ "ANALYTICAL REPORT - 4-MeO-BF" (PDF). European project RESPONSE. 
  4. ^ Jane Mounteney; Isabelle Giraudon; Gleb Denissov; Paul Griffiths (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". International Journal of Drug Policy. 26 (7): 626–631. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511. 
  5. ^ Anders Helander; Matilda Bäckberg; Olof Beck (April 2016). "Intoxications involving the fentanyl analogs acetylfentanyl, 4-methoxybutyrfentanyl and furanylfentanyl: results from the Swedish STRIDA project". Clinical Toxicology. 54 (4): 324–332. doi:10.3109/15563650.2016.1139715. PMID 26850293. 
  6. ^ "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015. 
  7. ^ "Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I". Federal Register. 1 February 2018. 

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