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Chaldene (// kal-DEE-nee; Greek: Χαλδηνή), also known as Jupiter XXI, is a retrograde irregular satellite of Jupiter. It was discovered by a team of astronomers from the University of Hawaii led by Scott S. Sheppard, et al., in 2000, and given the temporary designation S/2000 J 10.
Chaldene is about 3.8 kilometres in diameter, and orbits Jupiter at an average distance of 22,713 Mm in 699.327 days, at an inclination of 167° to the ecliptic (169° to Jupiter's equator), in a retrograde direction and with an eccentricity of 0.2916.
It belongs to the Carme group, made up of irregular retrograde moons orbiting Jupiter at a distance ranging between 23 and 24 Gm and at an inclination of about 165°.